Article: Comparing Oxygen Testing Methods

The headspace oxygen concentration is a critical quality parameter for oxygen-sensitive products. Accurate determination of the oxygen concentration is important across the product life cycle. Traditional methods for determining headspace oxygen levels in parenteral containers, such as electrochemical methods or gas chromatography, are slow and destructive. The analysis is both time and resource intensive and these conventional techniques are difficult to implement at- or in-line for immediate feedback about the filling process.

This article describes several case studies comparing non-destructive Laser-based Oxygen Headspace analysis with Electrochemical Oxygen analysis and Gas Chromatography.