Raised Stopper Detection in Freeze Dried Vials: Visual Inspection vs. Headspace Inspection

The use of coated stoppers for sealing product vials requires special attention to container closure integrity. This poster describes a container study done after a potential closure issue was identified in demonstration batches of a lyhophilized product.

Download to view data revealing issues with a vial/stopper combination, specifically related to the use of a coated stopper.