Our innovative products
Non-destructive headspace analysis, from development through routine QC
Robust and portable, our user-friendly platforms support development, manufacturing, and quality control. Additionally, our automated solutions are designed for flexibility, small footprint, and with patented configurations for continuous calibration monitoring during an inspection run.
Verifying container closure integrity, headspace gas composition, or product moisture can all be done rapidly and non-destructively with laser-based headspace analysis.
Proven technology benchtop headspace analyzers
The LIGHTHOUSE FMS series applies laser-based headspace analysis and measures the gas or moisture composition in the headspace above your product within seconds, without opening, or damaging the product in the container. Because samples remain intact, you can retest the same vial over time, screen 100% of a batch, or feed the same containers into stability studies.
The FMS line covers four measurement types, each purpose-built for a specific application:
- FMS-Oxygen — for purge validation, headspace monitoring of oxidation-sensitive formulations, and CCI testing of freeze-dried products
- FMS-Carbon Dioxide — as part of our general CO₂-based container closure integrity tester and for automated media fill inspection
- FMS-Moisture/Pressure — vacuum and pressure-based CCIT, plus lyophilized product moisture determination as an alternative to Karl Fischer titration or Loss on Drying
- FMS-Water Activity — water activity and moisture exchange measurement for oral solid dosage, freeze-dried, and powder product
All share the same compact benchtop footprint, 21 CFR Part 11–compliant software, and NIST-traceable calibration standards, enabling an easy switch between applications without a new learning curve.
Our Line of Benchtop Instruments
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CCI Tester
Dye ingress and other probabilistic CCI tests leave leak detection… — Read more -
FMS-Carbon Dioxide Headspace Analyzer
The FMS-Carbon Dioxide is a non-destructive headspace carbon dioxide analyzer… — Read more -
FMS-Water Activity Headspace Analyzer
The FMS-Water Activity Analyzer is a non-destructive gas analyzer for… — Read more -
FMS-Moisture/Pressure Headspace Analyzer
The FMS-Moisture/Pressure is a non-destructive headspace moisture and pressure analyzer… — Read more -
FMS-Oxygen Headspace Analyzer
The FMS-Oxygen is a non-destructive headspace oxygen analyzer from LIGHTHOUSE,… — Read more
Scaling headspace inspection from bench to line
A benchtop analyzer proves a method works. Getting that same measurement onto your production line, or across the large sample sets your process development studies require, is a different problem — one that manual handling struggles to solve without adding time, variability, or additional headcount.
LIGHTHOUSE’s automated platforms extend the same laser-based headspace measurement principle across three levels of throughput:
PULSAR is a fully automated 100% inspection system for your production line, measuring headspace oxygen, pressure, and CO₂ on every container at up to 300 containers per minute. It is built for 100% CCI inspection of freeze-dried and modified-headspace product, as well as automated media fill inspection, with a compact, single-dial footprint designed to move into existing plant space.
ILLUMINATOR brings the same 100% inspection principle to process development and aseptic process simulation, characterizing nitrogen purge efficiency, lyophilizer moisture performance, and media fill vials at a scale suited to development and qualification studies rather than full production runs.
The FMS Automation Module pairs a robotic sample handler with your existing FMS-Oxygen, FMS-Carbon Dioxide, or FMS-Moisture/Pressure analyzer, automating sample loading and unloading to reach throughput of up to 300 samples per hour. It turns a benchtop analyzer into a higher-throughput system for statistically significant sampling, without the cost or footprint of a full inline platform.
Across all three, measurement data is written directly into the LIGHTHOUSE GxP database, keeping your audit trail, batch reports, and Part 11 compliance intact as you scale.
