Several glass vials containing freeze-dried pharmaceutical product in a LIGHTHOUSE laboratory.

Moisture Determination

Controlling residual moisture is key in ensuring the quality and shelf life of lyophilized drugs, sterile powders, and solid dosage forms. Inspect 100% of your products using non-destructive headspace moisture analysis, to give you full data-driven insight into process efficiency and consistency.

LIGHTHOUSE headspace moisture analysis enables

  • Fast and non-destructive moisture analysis
  • Direct measurement of harmful reactive water
  • 100% inspection of drug product
  • Replacement of tedious indirect moisture measurements
  • Data-driven control of drying processes
  • Release of non-compromised drug product only

Analyze moisture levels non-destructively in 100% of your products

Consistent and efficient drying of drug products is complex, but with headspace analysis, we can simplify moisture control. When it comes to drug efficacy and shelf life, unbound water is the key factor that affects product quality.

Traditional residual moisture analysis methods are destructive, slow, and unable to measure unbound or reactive water directly. LIGHTHOUSE offers fast, non-destructive headspace moisture analysis that measures reactive water directly, providing accurate, reliable, and more relevant data.

 

 

LIGHTHOUSE Headspace Moisture Pressure Analyzer for lyophilized products

We help you select the best primary package

Over time, moisture will permeate into your product package, affecting product stability. To protect your product, you therefore need both optimal moisture control and the right primary packaging to minimize moisture permeation.

Using non-destructive headspace moisture analysis, we can help you select the best packaging components. Our Analytical Service labs also offer long-term stability studies under accelerated conditions, ensuring your product stays protected over time.

 

 

 

 

 

 

Several glass vials with red caps filled with freeze-dried product to be tested for container closure integrity.

Speed up process development and optimization

Achieving consistently dry, high-quality products requires robust process data, which conventional methods can’t deliver. With non-destructive headspace moisture analysis, you can gain deep insight into your freeze-drying efficiency.

We help customers analyze entire batches in under a day, providing near-instant feedback during process optimization. Rely on our experts for guidance and on-site measurement support, ensuring your process development is fast, efficient, and data-driven.

 

 

 

 

Person operating a 100% non-destructive headspace inspection machine.

Ensure no out-of-specification product is released

Even the best processes can fail, and when they do, you need a reliable partner who can help. For decades, we’ve helped companies with emergency headspace inspections on quarantined batches, saving valuable products by separating compromised containers.

Our non-destructive 100% inspection method ensures no product is lost and only in-spec products are released. We can be on-site and operational with a fully validated inspection machine within weeks, providing expert support throughout the process.

 

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