A small, mobile automated headspace inspection platform
The Illuminator Headspace Inspection System delivers automated, 100% inspection of headspace oxygen, moisture, and carbon dioxide concentrations for process development, filling line and freeze dryer qualification, vacuum maintenance and automated media fill inspection.
One system, built for when measurement speed and certainty are needed
- Automate media fill inspections Replace manual, operator-dependent visual checks during aseptic process simulations with 100% automated inspection and run at up to 100 containers per minute.
- Accelerate nitrogen purge and freeze-dryer optimization Characterize nitrogen purge efficiency for oxygen-sensitive fills and map moisture content across every vial during freeze dryer performance qualification. Getting quick results means reaching the best process parameters faster.
- 100% CCI inspection for low-volume, high-toxicity products For ADCs and other high-potency products where small batch sizes make statistical sampling hard to justify, inspect every container instead of a subset. Suitable for tubing or molded vials, amber or clear, from 2R to 100R.
- Fast turnaround on out-of-specification CCI results When a batch is held on a CCI result, clear the investigation queue using Illuminator, without pulling your team off routine work for days.
Take your headspace studies anywhere in the plant
- Four permanently mounted Standard Calibration Vials continuously verify sensor calibration during operation, not just at startup
- Runs on single-phase power and a minimal nitrogen supply — no specialized utilities required
- Compact, mobile design moves between locations in the plant for different studies and applications
- 21 CFR Part 11 compliant database logs every measurement, alarm, and settings change, with exportable Batch, Measurement, Alarm, and Audit Trail reports
- Tray load and unload simplify sample handling during development and qualification studies
Why choose LIGHTHOUSE?
- Automated, deterministic 100% inspection
- Patented laser absorption technology, originally developed with funding from the FDA
- LIGHTHOUSE introduced laser headspace technology to the pharmaceutical industry more than 30 years ago and holds the largest installed base of laser-based headspace systems worldwide
- Continuous, in-process calibration verification via permanently mounted Standard Calibration Vials
- Compact, mobile platform moves to where the study is, instead of a fixed line installation
- Minimal utility footprint — single-phase power and either nitrogen or compressed dry air
- Full 21 CFR Part 11 compliant reporting, from batch records to audit trails
In action: Illuminator for automated media fill inspection
ILLUMINATOR
SPECIFICATIONS
Structure
Compact single dial machine, up to two measurement sensors, tray load and un-load
Container Sizes
Vials ranging from 2R to 100R
Container Compatibility
Tubing or molded; amber or clear
Maximum Throughput
100 containers per minute
Software
21 CFR Part 11 compliant database
Dimensions
180cm x 90cm x 120cm
Power Requirements
200–240 VAC 1-phase, 15 amp, 50/60 Hz
Compressed Nitrogen or Dry Oxygen
25 slpm @ >3.5 barg
Trusted by the Pharmaceutical Industry
- More than 30 years of experience in laser-based headspace analysis
- Used by all of the top 10 global pharmaceutical companies
- GMP certified services aligned with global regulatory expectations
Learn more about...
-
Automated Media Fill Inspection
Manual inspection of media-filled vials for contamination is tedious, time-consuming,… — Read more -
Equipment Lease
Our flexible lease option allows clients to plan for short… — Read more -
Container Closure Integrity Testing
LIGHTHOUSE provides rapid, non-destructive Container Closure Integrity Testing (CCIT) for… — Read more
Get in touch with Rick
Do you have questions about our services or need expert advice for your project? Our dedicated team is here to help. Contact us today to learn how we can support your specific needs.
