The USP<922> Water Activity was published as a general chapter in May-2021. As water activity increases, more loosely bound water is available to accelerate undesirable chemical, physical and microbiological reactions than can cause stability failures. Measuring the change in the equilibrium relative humidity of tablets and capsules inside the blister packs and bottles will provide the information required to understand long term stability.
This webinar includes:
- How does relative humidity and water activity change inside the primary packaging over time?
- How does water activity correlate to microbial growth, degradation and dissolution failures?
- What information does water activity provide that Karl Fischer cannot provide?
Download the webinar to gain insight on the technical and regulatory justification to add water activity measurements into pharmaceutical stability protocols.